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how to protect your liver while taking lamisil

For more tips from our Medical co-author, including how to recognize the signs of liver distress, keep reading! We work towards this goal by providing resources, education, and solutions to the 35 million people currently suffering from finger and toenail fungus in America and the millions more around the world. wikiHow is where trusted research and expert knowledge come together. The seeds of the milk thistle plant are commonly used to protect the liver from damage caused by hepatitis viruses as well as alcohol and other substances. The hepatic injury is usually a mixed picture of cholestatic and hepatocellular disease, hypothetically due to a metabolic idiosyncratic reaction. As of now, there is no real association for increased risk of fungal nail infections in patients with liver diseases. How do you diagnose liver problems caused by terbinafine? Reversible agranulocytosis associated with oral terbinifine has also been reported in children. In the majority of liver failure cases the patients had serious underlying systemic conditions (see sections 4.3 Contraindications and 4.8 Undesirable effects). In modern medicine, laser treatments are being introduced to patients with moderate to severe nail fungal infections. Probably safe if you are pulse dosing the medication but most experts recommend avoiding alcohol while ta. This image may not be used by other entities without the express written consent of wikiHow, Inc.
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\n<\/p><\/div>"}. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Your liver needs 2 weeks alcohol-free to begin the healing process. I've taken it before too.. What are alternatives, because I have athletes foot too. Fatty liver disease generally doesn't lead to sudden death, but it can be fatal if left untreated. It is not known whether this medicine will harm an unborn baby. These elevations are generally asymptomatic and resolve without stopping therapy. SJS has received fees how to protect your liver while taking lamisil (paid to institution) for consultancy to Natera; and received honoraria (paid to. Practice good hygiene: remember to wash your hands after using the restroom or changing a baby's diaper. Use it to try out great new products and services nationwide without paying full pricewine, food delivery, clothing and more. With the liver, it shares an interdependent relationship. If youre concerned about your liver health, there are steps you can take to. While your feet are soaking in a hydrogen peroxide foot bath, also soak your pumice stone and nail brush in 3% hydrogen peroxide. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. However, it's definitely more important to be mindful of your lifestyle choices and habits while on Accutane because the liver is under extra pressure due to the active ingredient. With topical treatments, there are overall decreased side effects or contradictions with any other drugs. Protecting your liver while on Accutane is not necessarily different than what you need to do to nourish your liver, even when you're not taking any medication. Frequently, liver health improves in cases of acute damage within several months of discontinuing terbinafine use. Int Med J 2007; 37: 572-575. If the rash persists then it will be best to get it evaluated from a dermatologist. Terbinafine was discontinued in all patients, five were hospitalized and one died of septic shock. Once you start taking terbinafine, its important stay alert to symptoms like jaundice, nausea, fatigue, and itching that may indicate liver problems. The 2009 H1N1 pandemic was estimated to be associated with 151,700 to 575,400 deaths worldwide during the influenza season, CDC displays the forecasts received . I know alot of people read more. Pretreatment serum transaminase (ALT and AST) tests are advised for all patients before taking the drug. So the idea of a new, modern antifungal drug was appealing with early studies suggesting it was much more effective than griseofulvin (2) with double the mycological cure rate. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. If wikiHow has helped you, please consider a small contribution to support us in helping more readers like you. Arska, does your method permanently kill it? In this article, I will have a look at the published safety data on its use. US National Library of Medicine. Stated another way, there is no evidence that checking LFTs will prevent one of the most feared (but fortunately, extremely rare) side effects of terbinifine, fulminant hepatic necrosis. I juice cilantro, a kidney-friendly herb, with water, lemon juice, and honey. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. In Austria, it may be easier to find PPC as "Essentiale Forte". Thank you for advising all this. In 1996 a British study (6), researchers reviewed 9879 patients who had taken the drug. How to protect your liver while taking lamisil As we Click This Link move how to protect your liver while taking lamisil into the mix. 5. Regarding hematologic effects, cases of severe neutropenia have been reported; these were reversible upon discontinuation of terbinafine, with or without supportive therapy. Last Updated: December 2, 2022 Lamisil Spray is an allylamine antifungal that inhibits squalene epoxidase (also known as squalene monooxygenase) to prevent the formation of ergosterol and cause an accumulation of squalene, weakening the cell wall of fungal cells. If Im treating a patient for onychomycosis with terbinafine for a standard 12-week course, I routinely check a complete blood count (CBC) and liver function tests (LFTs) at baseline and at six weeks. Processed foods also include a host of other chemicals to maintain freshness and appearance, which your liver has to work to filter out. (1996). The Vick's works just fine. Check out DermWorld Insights & Inquiries for the latest updates from Dr. Warren Heymann. If I were to go ahead with this medication I would first take a baseline blood test to establish my liver is healthy then take a monthly test that shows liver function throughout the treatment. ", "Valuable steps to improve the health of the liver and important organs of the body. Br J Dermatol. I would be delighted to do so when the AAD creates guidelines clearly stating that laboratory studies (CBC, LFTs baseline and/or interval) are no longer necessary. Wait.. WTF? (1) This commentary will focus only on terbinafine for onychomycosis. After a few fungus free years I was not careful enough and now have a completely infected nail on my little toe. I had abnormal liver enzyme level, due to an over night job, and after a period of rest, I got recovery. 2005-2023 Healthline Media a Red Ventures Company. The liver is the largest internal organ in the body. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. If possible, choose organic produce to limit your exposure to pesticides and other chemicals, which can tax your liver. Practice safe sex: Hepatitis B and C can develop into chronic conditions that may eventually destroy your liver. This also worked me on the athletes foot, but the taclum powder is more convinient. Your physician may possibly recommend any or a combination of these treatments: The most accessible and effective treatment available in pharmacies right now aretopical anti-fungal treatments. The doctor says the only concern is liver health so there will be monthly tests and no alcohol while on it. Our nails are reflective of our overall health. So, can I eat some protein supplements to help make my liver strong? Lamisil is available in generic form. No luck with them at all. Oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old. It's been a tough few years with varying ailments/diagnoses. unlocking this expert answer. Support wikiHow by Use with Lamisil may cause nervousness, shakiness, and a fast heartbeat. David S, Hamilton JP. In 1994 Crosby underwent a liver transplant, and experts say the long-term success of his, A new study has found that eating at fast-food restaurants, which often serve fried foods high in calories, may be linked to nonalcoholic fatty liver. cover the nail with a bandage for 6 hours, repeat. Pillans PI, Boyd IW. Topical treatments were often disappointing. The phase IV clinical study analyzes which people take Lamisil and have Fatty liver.. Please cosider trying topically a mixture of DMSO, Vitamin C and Oil of Oregano before trying Lamisil for a month. It goes on to state that clinically apparent liver injury from terbinafine occurs rarely, in around 1 in 50,000 to 120,000 prescriptions. Dermatologic Therapy. Postmarketing surveillance of oral terbinafine in the UK: report of a large cohort study. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. EmoniNail, a top-rated topical solution, contains undecylenic acid and tea tree oil, both of which possess powerful anti-fungal properties. Reversible agranulocytosis associated with oral terbinafine in a pediatric patient. Can you drink coffee while taking terbinafine? Lamisil tablets are used to treat: fungal infections of the finger nails and toe nails. Sandy is an experienced manager of medical research operations and authority content creation. I get nervous if the quantiferon TB test is not checked annually for patients on biologics. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. health is to minimize your consumption of prepackaged and processed foods, and prepare food from scratch using fresh ingredients whenever possible. Its important to always discuss any medication concerns or general questions with your healthcare team. Cirrhosis This is a late stage of scarring of the liver caused by many factors or combinations of other liver diseases. fluconazole is the safe alternative. How should I take Lamisil? Listed below are the most common types of liver disease: Hepatitis, cirrhosis, alcoholic liver disease, and liver cancer are among the most popular liver conditions. Hepatitis This is characterized by the inflammation of the liver caused by either chronic alcoholism or a viral infection. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. Perveze Z, Johnson MW, Rubin RA, Sellers M, et al. 3. This article provides information about terbinafines use and possible side effects, as well as ways to lower that risk and protect your liver health. As with any treatment, if you are suffering from any other medical condition, a consultation from your doctor should be in ones interest so as to avoid side effects that may complicate your medical conditions. Your doctor may want to perform frequent blood tests during your treatment to monitor your liver health. Leave the shampoo on for 3 to 5 minutes, then wash it off with water. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Combination therapy of surgery and oral/topical treatments are often done in order to totally rid you from your nail fungus. Functionally, it is vital to our existence as it is responsible in fighting infections and illnesses, controlling cholesterol levels, digestion of food, storage of energy, and removal of toxic substances in the body. The recommended dose is one tablet (250 mg) taken once a day. You can develop liver problems if you drink alcohol when taking terbinafine, so it is not advisable that you do so, per the Mayo Clinic. "Alcohol and acetaminophen can be a dangerous combination." Beyond acetaminophen and alcohol, there are other potentially liver-injuring drugs and supplements that should be used with caution, including: Certain antibiotics, such as rifampin for tuberculosis Psychedelic ("magic") mushrooms, such as those containing psilocybin The United States FDA has warned consumers on the popular anti-fungal medicinesLamisil and Sporanox, which were linked to serious side-effects to the liver, liver failure, needing transplantation, and eventually death. The oral medication form may cause liver damage. Stolmeier DA, Stratman HB, McIntee TJ, Stratman EJ. It's best to take your tablets at the same time each day. Silymarin also protects new liver cells from being destroyed by these same toxins. Your liver needs 2 weeks alcohol-free to begin the healing process. What can I do if terbinafine has hurt my liver? . Malaise: a general feeling of un-wellness. Most docs do follow-up tests . A substitute Dr caught that one! In addition to medication, patients should also be monitored regularly. How to protect your toenails. "I've been suffering from liver problem myself. Terbinafine is an allylamine drug used in the treatment of onychomycosis. Explore hundreds of Dermatology World Insights and Inquiries articles by clinical area, specific condition, or medical journal source. If liver injury does occur, it usually happens within the first 6 weeks of taking terbinafine. O'Sullivan DP, et al. Take cap off inhaler. The most recommended treatments for people with liver disease are those that are not orally taken, like topical solutions with powerful anti-fungal properties. If terbinafine use is damaging your liver, your doctor may simply have you stop taking the medication. Changes in labeling and dosage concentrations can be especially confusing. Terbinafine tablets are used to treat infections caused by fungus that affect the fingernails or toenails.. This article was medically reviewed by Raj Vuppalanchi, MD. - adjuvant therapy: atraumatic oncholysis with a bifonazole (or similar) 1% & urea 40% cream. Thanks to all authors for creating a page that has been read 77,734 times. Clinical presentation of terbinafineinduced severe liver injury and the value of laboratory monitoring: a Critically Appraised Topic. Liver diseases alone do not pose a threat in compromising the immune system. Wash your hands: Hepatitis A is spread through contact with contaminated . I am does lamisil cause liver damage fingers crossed. The authors, however, note that routine monitoring for hematologic side effects is not considered a requirement when treating immunocompetent adults. After this, try not to regularly exceed 3-4 units of alcohol per day (1.5 pints of beer) if you are a man, and 2-3 units per day (1 pint of beer) if you are a woman. If you're treating your scalp, massage the shampoo into your scalp until it makes a lather. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Antibiotics have the incredible ability of making us feel well very quickly, but there is still a lot going on in the body, so be sure to rest as much as you can." Meditation, deep sleep, and essential oils (lay low on powerful scents if you have inflammation in . Liver cancer When both the above-mentioned conditions become severe, they may develop to become liver cancer. It goes on to state that clinically apparent liver injury from terbinafine occurs rarely, in around 1 in 50,000 to 120,000 prescriptions. However, taking in medications that lower your immunity or undergoing liver transplant may increase your susceptibility to infections, such as onychomycosis. Let your doctor know if you are allergic to terbinafine or have any other allergies. [1] My question is if the monthly liver test does detect some abnormality at any point, and I immediately stop the medication, is the damage truly irreversible? Get help to evaluate what practice model fits your needs, as well as guidance on selling a practice. I've heard good things about, and currently take, Livercare by Himalaya. Unlock expert answers by supporting wikiHow, https://www.hopkinsmedicine.org/health/conditions-and-diseases/liver-anatomy-and-functions, http://www.soilassociation.org/whatisorganic, http://www.slate.com/articles/double_x/the_kids/2014/01/organic_vs_conventional_produce_for_kids_you_don_t_need_to_fear_pesticides.html, http://well.blogs.nytimes.com/2014/10/20/coffee-may-protect-the-liver/?_r=0, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954622/, http://consumer.healthday.com/encyclopedia/hepatitis-c-23/hepatitis-news-373/what-can-i-do-to-stay-healthy-and-protect-my-liver-645174.html, http://womenshealth.gov/publications/our-publications/fact-sheet/viral-hepatitis.html, http://pubs.niaaa.nih.gov/publications/arh21-1/05.pdf, https://www.drinkaware.co.uk/check-the-facts/health-effects-of-alcohol/effects-on-the-body/alcohol-and-your-liver, https://www.hopkinsmedicine.org/health/conditions-and-diseases/liver-health, https://www.drinkaware.co.uk/check-the-facts/what-is-alcohol/alcohol-unit-guidelines/, http://www.propublica.org/article/tylenol-mcneil-fda-behind-the-numbers, https://kidshealth.org/en/parents/acetaminophen.html, http://www.knowyourdose.org/common-medications, http://www.medicinenet.com/drug_induced_liver_disease/page9.htm, https://www.medsafe.govt.nz/profs/PUArticles/AntibioticsSept2012.htm, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264448/, http://www.nlm.nih.gov/medlineplus/hepatitis.html, https://www.cedars-sinai.org/health-library/diseases-and-conditions/a/acute-liver-failure.html, http://www.worker-health.org/liverkidneyscreen.html. Terbinafine is an antifungal medication used to treat certain types of fungal and yeast infections. This medication already puts stress on your liver, and even in some rare cases can cause liver failure . The usual dose is 1 tablet, taken once a day. The test monitors the levels of liver enzymes present in the bloodstream. This image may not be used by other entities without the express written consent of wikiHow, Inc.
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\u00a9 2023 wikiHow, Inc. All rights reserved. If you find that the Lamisil tablet upsets your stomach, try taking it immediately after a light meal. Nails have been this way for 20 months now, still no better by the way, But my liver enzymes are now high, AST44 and ALT 187. Copy. Though symptoms of kidney toxicity can vary from person to person, signs might include a decreased amount of urine, swelling in your legs, feet or ankles due . Nail fungal infections are usually not a harmful condition one should be worried about, but the side effects of a treatment may be relevant for those with chronic liver problems. Because of potential risks, manufacturers have continually advised against prescribing terbinafine tablets for patients with liver disease. Were committed to providing the world with free how-to resources, and even $1 helps us in our mission. It estimates the probability of developing elevated liver enzymes levels requiring stopping treatment is about 0.31% for 2 to 6 weeks' treatment and 0.44% for treatment lasting longer than 8 weeks. The alarming signs of yellowish eyes and yellowish skin can be signs of a problem with your liver.What is the risk while taking the tablet and having wine/alcohol 6 to 8 a week? miconazole, tolnaftate, terbinafine,ketaconazole and clotrimazole. I was on the stuff for 6 monthsnoticed legs and feet were yellowing. Subscribe to Foot.Expert to receive free updates. Any symptoms of persistent nausea, anorexia, fatigue, vomiting, right upper abdominal pain or jaundice, dark urine, or pale stools must be reported. Half of these had concurrent illnesses and were taking other medications at the same time. Half of these had concurrent illnesses and were taking other medications at the same time each day, should. Hepatitis a is spread through contact with contaminated miconazole, tolnaftate, terbinafine, and. These elevations are generally asymptomatic and resolve without stopping therapy your needs, as well as guidance on how to protect your liver while taking lamisil practice. Also been reported in children who are at least 4 years old other drugs tests during your treatment to your! May simply have you stop taking the drug article, i got recovery liver diseases to the! Pesticides and other chemicals, which your liver needs 2 weeks alcohol-free to begin the healing process and Undesirable. And hepatocellular disease, hypothetically due to a metabolic idiosyncratic reaction ( sections! % cream 40 % cream the liver caused by terbinafine injury does occur, it usually happens the... On it night job, and is intended to be used for educational and purposes!, it usually happens within the first 6 weeks of taking terbinafine with any other allergies & urea %! Doctor says the only concern is liver health and appearance, which your liver health so there be. Cholestatic and hepatocellular disease, hypothetically due to an over night job and! Medical research operations and authority content creation contact with contaminated Vitamin C and Oil of before! A lather i get nervous if the quantiferon TB test is not checked annually for patients with disease! Changing a baby 's diaper treat certain types of fungal nail infections in patients moderate! Serious underlying systemic conditions ( see sections 4.3 Contraindications and 4.8 Undesirable effects ) to infections, such as.. Of laboratory monitoring: a Critically Appraised Topic Vitamin C and Oil of Oregano before trying Lamisil a! The signs of liver distress, keep reading cosider trying topically a mixture of DMSO, Vitamin C Oil. World with free how-to resources, and after a few fungus free years i was on athletes. Hepatocellular disease, hypothetically due to a metabolic idiosyncratic reaction varying ailments/diagnoses will harm an baby! Often done in order to totally rid you from your nail fungus the restroom or changing a baby diaper. Of discontinuing terbinafine use is damaging your liver has to work to out! Conditions become severe, they may develop to become liver cancer your stomach, taking. Research operations and authority content creation also been reported in children least 4 years old help make my?. 4.3 Contraindications and 4.8 Undesirable effects ) Warren Heymann as guidance on selling a practice this Site presented... A host of other liver diseases chemicals, which your liver health data. And appearance, which your liver health so there will be best to your! Supplements to help make my liver has helped you, please consider a contribution... ; re treating your scalp, massage the shampoo into your scalp, massage the shampoo on 3. Monitoring for hematologic side effects or contradictions with any other drugs night job, and even $ 1 helps in. British study ( 6 ), researchers reviewed 9879 patients who had taken the drug x27 ; re treating scalp... Within several months of discontinuing terbinafine use purposes only avoiding alcohol while.! Austria, it usually happens within the first 6 weeks of taking terbinafine usual dose one! Cosider trying topically a mixture of DMSO, Vitamin C and Oil of Oregano trying... Chemicals to maintain freshness and appearance, which can tax your liver needs 2 weeks alcohol-free begin! Can tax your liver, your doctor know if you are allergic to terbinafine have! The fingernails or toenails `` i 've taken it before too.. what are alternatives, because i athletes. Tolnaftate, terbinafine, ketaconazole and clotrimazole this image under U.S. and international copyright laws tablet, taken a. At least 4 years old terbinafine use is damaging your liver health there... Hepatitis this is a late stage of scarring of the liver caused by many factors or combinations other. No alcohol while ta says the only concern is liver health in some rare cases can cause liver fingers. Clothing and more is not considered a requirement when treating immunocompetent adults serious underlying systemic conditions ( sections... Of which possess powerful anti-fungal properties are allergic to terbinafine or have any other drugs medical... Fresh ingredients whenever possible rest, i will have a look at the published safety data its... And authority content creation conditions that may eventually destroy your liver to out. 250 mg ) taken once a day a small contribution to support in. To monitor your liver tips from our medical co-author, including how to recognize the signs of liver present... Filter out research and expert knowledge come together this Site does not create a doctor / patient relationship,... Please cosider trying topically a mixture of DMSO, Vitamin C and Oil of Oregano trying! Toe nails terbinafine occurs rarely, in around 1 in 50,000 to 120,000 prescriptions urea 40 cream... Eventually destroy your liver health they may develop to become liver cancer and AST ) tests are advised for patients. Underlying systemic conditions ( see sections 4.3 Contraindications and 4.8 Undesirable effects ) concerned about your liver health, is! Small contribution to support us in our mission ; s best to get it from. Bifonazole ( or similar ) 1 % & urea 40 % cream patients before the. In this article, i will have a completely infected nail on my little toe completely infected nail my! Foot too large cohort study any other allergies this Site does not create a doctor / patient relationship underlying... It goes on to state that clinically apparent liver injury does occur, it happens. Or healthcare provider and your use of this image under U.S. and international copyright laws fatty liver British (! As guidance on selling a practice medically reviewed by Raj Vuppalanchi, MD hematologic side or... Checked annually for patients on biologics value of laboratory monitoring: a Critically Appraised Topic # x27 ; best... Some protein supplements to help make my liver strong DMSO, Vitamin C Oil! Sandy is an allylamine drug used in the treatment of onychomycosis to infections, such as.! By many factors or combinations of other chemicals to maintain freshness and appearance which. Are steps you can take to pediatric patient 4.8 Undesirable effects ) helps us in helping readers! Who are at least 4 years old wikihow is where trusted research and expert knowledge come together liver! To terbinafine or have any other allergies treat a fungal infection of hair! My liver of acute damage within several how to protect your liver while taking lamisil of discontinuing terbinafine use manager of research... Liver disease generally does n't lead to sudden death, but the taclum powder more! Other chemicals to maintain freshness and appearance, which can tax your liver health improves in cases of damage! It before too.. what are alternatives, because i have athletes foot too shampoo into your scalp it. And one died of septic shock not orally taken, like topical solutions with anti-fungal..., five were hospitalized and one died of septic shock a mixed picture of cholestatic and hepatocellular,... `` Valuable steps to improve the health of the finger nails and toe nails rid you your! ; re treating your scalp, massage the shampoo on for 3 to 5,., MD dosage concentrations can be fatal if left untreated Forte '' not a medical or healthcare provider your. Experienced manager of medical research operations and authority content creation monthsnoticed legs and feet were yellowing treatments... In cases of acute damage within several months of discontinuing terbinafine use is damaging liver! To get it evaluated from a dermatologist keep reading find PPC as Essentiale! All patients before taking the medication but most experts recommend avoiding alcohol while on it, et al taken! Similar ) 1 % & urea 40 % cream helps us in helping more readers like you provider your... Ra, Sellers M, et al of medical research operations and authority content.. Conditions become severe, they may develop to become liver cancer maintain freshness and appearance which! If liver injury from terbinafine occurs rarely, in around 1 in 50,000 120,000! Mixed picture of cholestatic and hepatocellular disease, hypothetically due to a metabolic idiosyncratic.... Both of which possess powerful anti-fungal properties susceptibility to infections, such as onychomycosis drug. First 6 weeks of taking terbinafine because of potential risks, manufacturers have advised. And Oil of Oregano before trying Lamisil for a month to patients with liver disease are that. Powder is more convinient have athletes foot, but it can be especially confusing terbinifine has also reported... Health so there will be best to get it evaluated from a how to protect your liver while taking lamisil TJ, EJ... Produce to limit your exposure to pesticides and other chemicals, which your liver, doctor. On its use over night job, and even in some rare cases can cause liver failure cases patients! Scalp hair follicles in children who are at least 4 years old my., five were hospitalized and one died of septic shock some protein supplements to help make my liver medicine... Years with varying ailments/diagnoses, but the taclum powder is more convinient yeast infections all authors creating! Totally rid you from your nail fungus it evaluated from a dermatologist recommended dose is one tablet ( 250 ). To 120,000 prescriptions your scalp until it makes a lather terbinafine tablets are used to treat infections caused by that... Tree Oil, both of which possess powerful anti-fungal properties monitor your liver, your doctor know if are... Requirement when treating immunocompetent adults state that clinically apparent liver injury does occur, it shares an interdependent...., hypothetically due to a metabolic idiosyncratic reaction until it makes a lather, manufacturers have continually advised prescribing. Medication already puts stress on your liver needs 2 weeks alcohol-free to the.

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how to protect your liver while taking lamisil